Develop and validate a common set of standardised, modular and scalable EMA resources for all actuators (flight control, high lift, main landing gear, door, thrust reverser) and all types of aircraft.

The aim of AIRPOXY is to reduce production & MRO costs of carbon composite parts in aeronautics by introducing a new family of enhanced composites that preserve all the advantages of conventional thermosets, while showing new unprecedented features such as Re-processability, Reparability and Recyclability.

Implement the necessary partnerships and perform efficient collaborative research to achieve the exploitable results strengthening national and European competitiveness

Go on carrying research on top of the existing SCARLETT state-of-the-art in areas where innovations are likely to make the most of DME growth potential.

The project AUDIO will coordinate the Airspace User (AU) involvement in the demonstration of innovative airport operations functionalities designed to improve airport operations. It is designed to secure the involvement of additional end-users to perform operational demonstrations to confirm the benefits and increase awareness of promising solutions targeting specific operational scenarios and environments.

The CENTRELINE Project will demonstrate the proof of concept for a ground-breaking approach to synergistic propulsion-airframe integration. The concept consists of a dedicated propulsive device that entrains and re-energises the fuselage boundary layer flow in order to directly compensate the viscous drag effects in the fuselage wake field.

Implement the necessary partnerships and perform efficient collaborative research to achieve the exploitable results strengthening national and European competitiveness

Implement the necessary partnerships and perform efficient collaborative research to achieve the exploitable results strengthening national and European competitiveness

Develop the foundations for the Behavioural Digital Aircraft (BDA), taking experience and results from VIVACE, and integrating these into a federative system and building the BDA on top of them

Design, integrate and validate new engine concepts to reduce fuel consumption and CO2 emissions 7% beyond the ACARE 2020 objectives.

Electrified aircraft propulsion is the use of propulsors (propellers or fans) driven by electric motors to propel aircraft. The technology requires the development or refinement of several components to ensure the electric system supplies the electric power for propulsion efficiently while keeping electromagnetic emissions within safety limits. The EU-funded EASIER project is an interdisciplinary collaboration between researchers from different countries who will conduct research on multiple topics related to electric power systems. In particular, they will investigate filter systems that suppress electromagnetic interference (EMI) and lightweight electrical wiring interconnection systems that limit EMI generation. What is more, they will examine how to improve heat transfer from electrical systems to the aircraft exterior.

Design, develop and validate innovative technologies and architectures for aero-engine lubrification systems targeting increased efficiency and reduced cost, mass and engine Specific Fuel Consumption (SFC).

ENABLEH2 will mature critical technologies for LH2 based propulsion to achieve zero mission-level CO2 and ultra-low NOx emissions, with long term safety and sustainability. ENABLEH2 will tackle key challenges i.e. safety, infrastructure development, economic sustainability, community acceptance, and explore key opportunities through improved combustor design and fuel system heat management, to further minimize NOx emissions, improve energy efficiency and reduce the required volumes of LH2.

Focus on the low pressure system of ultra-high by-pass ratio propulsion systems (12 < BPR < 20) in conjunction with ultra high overall pressure ratio (50 < OPR < 70) to provide significant reductions in CO2 emissions in terms of fuel burn (-3% to -5%) and engine noise (-1.3 ENPdB). ENOVAL will focus on ducted geared and nongeared turbofan engines, which are amongst the best candidates for the next generation of short/medium range and long range commercial aircraft applications with an entry into service date of 2025 onward.

Electromagnetic Platform for lightweight Integration/Installation of electrical systems in Composite Electrical Aircraft. International Cooperation with Canada.

Contribute to reductions in aircraft engine fuel consumption with a targeted contribution of 1% reduction in SFC relative to engines currently in service.

Optimise the combustor-turbine interactions design to develop low-cost turbines and reduce SFC by 2%, HPT weight by 1.5% and accordingly engine cost by 3% compared to the results from the TATEF2 and AITEB2 projects

Deliver key enabling technologies for combustion emission reduction by developing improved design tools and techniques for modelling and controlling fuel sprays and soot.

FLHYSAFE’s ambition is to demonstrate that a cost efficient modular fuel cell system can replace the most critical safety systems and be used as an emergency power unit (EPU) aboard a commercial airplane providing enhanced safety functionalities. Additionally the project will virtually demonstrate that the system is able to be integrated into current aircraft designs respecting both installation volumes and maintenance constraints.

Implement the necessary partnerships and perform efficient collaborative research to achieve the exploitable results strengthening national and European competitiveness

Achieve high Technology Readiness Level (TRL6) for technologies (radar, detector) and capabilities (numerical models and tools, test facilities) developed as part of the project.

Implement the necessary partnerships to achieve the exploitable results strengthening national and European competitiveness

ICE GENESIS will provide the European aeronautical industry with a validated new generation of 3D icing engineering tools (numerical simulation tools and upgraded test capabilities), addressing App C, O and snow conditions, for safe, efficient, right first time, and cost effective design and certification of future regional, business and large aircraft, rotorcraft and engines.

Deliver novel combustor design methodologies to enable the design of low emissions combustors for new engines with advanced architectures and thermodynamic cycles and to integrate the latest low emission combustion design rules into the new design system.

Provide alternative fuel producers and, air framers and aero-engine OEMs with knowledge based screening tools.

Provide reliable methodologies to predict the stability of industrial low NOx combustors, as well as their ignition process from spark to annular combustion.

Improve core-engine thermal efficiency by increasing the overall pressure ratio (OPR) to up to 70 leading to a further reduction of CO2. Since NOx increases with OPR, combustion technologies have to be further developed, at the same time, to at least compensate for this effect.

Reduce or totally eliminate the most time-consuming and hence expensive non-added value operations, e.g. temporary assembly to check gaps, shimming, dismantling and tool handling.

Demonstrate the fast development and right-first-time validation of a highly-optimised composite airframe.

Establish the new industrial standard for commercial aircraft electrical system design, which will directly contribute to strengthening the competitiveness of the aeronautical industry

The need for the European aeronautics industry to use numerical simulation tools able to accurately predict ICI (Ice Crystal Icing) is therefore urgent and paramount, especially regarding the development of the new generation engines (UHBR, CROR, ATP) which are expected to be even more sensitive to the ICI threat than current in-service engines and for which comparative analysis methods will not be applicable any more. MUSIC-HAIC will complete the development of ICI models, implement them in existing industrial 3D multi-disciplinary tools, and perform extensive validation of the new ICI numerical capability through comparison of numerical results with both academic and industrial experimental data.

Investigate into the integration and the validation of the technologies that are required to enable Novel Aircraft Concepts (Low Noise Aircraft, Flying Wing, Low Cost Aircraft) to be assessed.

Provide technological breakthroughs for the field of aero engines efficiency and emissions.

Novel Integration of Powerplant System Equipment

Develop solutions that can play a significant role, enabling future products to meet the ACARE noise goals and improving current fleet noise levels through retrofitting.

Demonstrate how surface & spark discharge plasma actuators could be used to control aircraft aerodynamic flow

Implement the necessary partnerships and perform efficient collaborative research to achieve the exploitable results strengthening national and European competitiveness

Address the urgent need for European-led research in FS safety to develop the new generation of safer FS also offering the opportunity to reduce the current over-dependence on patented US technology.

Design, manufacturing and ground test of a contra-rotating open rotor propulsion system, demonstrating the feasibility of geared power transmission; the ability to control contra-rotating propeller blade pitch; and system noise levels equal to or better than current engines

Develop integrated technologies contributing to the engine sector ACARE environmental targets for the engines sector. Engine sector targets for Clean Sky are up to -20% CO2, up to -60% NOx, up to -20 EPNdB noise relative to year 2000 baseline

Carry out research leading to a conceptual breakthrough in IMA1G in order to define a scalable, reconfigurable fault-tolerant driven and secure new avionics platform.

Deliver active wing technologies and new aircraft configuration for breakthrough, new products

Demonstrate a carbon-neutral path for producing aviation fuel, compatible with current infrastructure, in an economically viable way.

Provide new advanced simulation methodologies in three specific fields: ice release, ice accretion with runback aspects and ice trajectory applied for aero propulsive systems to improve the knowledge of engine components behaviour under icing conditions.

Define a fully optimized avionic architecture for power and data transmission on unique path wires.

Solve the main limitations identified during past and ongoing projects appearing when lean combustion is pushed toward its maximum potential about NOx emissions reduction

Provide the necessary combustion prediction methods that enable the development of practical advanced combustion systems for future engines that will reduce emission levels and fuel consumption.

Radically change the way thermal studies are performed within aircraft design processes. It will create and manage a thermal aircraft architecture which today does not exist.

Provide a breakthrough in low noise and low emission engine architectures. Develop and validate novel lightweight and low noise technologies for commercial aircraft engines and thus provides a key step towards achieving the ACARE environmental goals in terms of CO2 and noise.

Optimisation of the entire aircraft design.

Define and coordinate the actions of research related to weather hazards with the aim to increase the robustness of the air transport system

Deliver research that is innovative, prepares rail for the future and takes into account results from previous research projects and programmes.

Develop a purpose-built, light weight L category electric vehicle that can be stacked together to gain space. Thanks to pioneering coupling systems, up to 8 ESPRIT vehicles can be nested together in a road train, 7 being towed, for an efficient redistribution of fleets and a smartly-balanced and cost efficient transport system.

Provide the European railway industry with a key step towards achieving full interoperability by providing the tools to assess the mechanical compatibility of pantographs and catenaries.

Reduce fuel consumption in shipping by 5% (with individual ships up to 10%) and thus reduce exhaust gas emissions.

Development of cost effective high performance track infrastructure, aiming at providing innovative solutions towards significant reduction of both investments and maintenance of infrastructure costs

Develop methods and tools that will contribute to a more cost efficient and effective improvement of European railway infrastructure based on whole life considerations.

Study and test solutions of "railway hybridization" on a tests platform

Reduce traffic deaths significantly and improving transport infrastructure efficiency.

Develop an industry standard evaluation framework for new Human Vehicle Interactions strategies with a specific focus on Human Machine Interfaces.

Develop tools to investigate and mitigate the effects of underwater noise generated by shipping, both in terms of the footprint of an individual ship (a "noise footprint") and of the spatial distribution of sound from a large number of ships contributing to the sound (a "noise map").

Investigate several State-of-the-Art propulsion system and new propulsion combined with advanced CFD for accurate analysis and design of the propulsors.

Offer new services and implement an innovative concept of exploitation of freight railway, more secure, more reliable and more reactive

Develop and demonstrate flexible and cost effective joining processes for rail products, and in particular for the more recently introduced bainitic rail steel grades, for which currently available conventional welding techniques have been shown to be inadequate.

Ultra Low emission Technology Innovations for Mid-century Aircraft Turbine Engines

Develop and validate a new type of all-in-one manufacturing technology combining, for the first time, in a single piece of equipment, 3D freeform printing and ultra-precision 3D assembly. This highly flexible and scalable facility will empower microsystem manufacturers - and in particular SMEs - to effectively produce highly miniaturised Smart Products-in-Package (SPiPs) both in small series and high-throughput production of large parallel batches.

The HOPES project aims at developing an intelligent multimedia platform providing innovative social e-services for European elderly persons and their social entourage (as carers / supporters and ICT tutors when needed).

Build a european vision and roadmap to address the challenges of the new generation of massively parallel systems.

Developed a new innovative technique and tools for the parameterisation of EMC design through simulation on parallel computers with message passing approach

Support 21 Technology Transfer Nodes that transfer high performance computing and networking technology to the European industry through 180 projects, including over 600 companies

Framework for running multi-site high performance computing environments using an open portable CORBA architecture

Drive scientific and technological breakthroughs in the domain of software security. STANCE will define, implement and validate a set of program analysis tools capable of verifying the security of complex software systems made in C, C++ and Java.

Develop a webmining technology able to answer professional needs for searching and analysing information accessible on the web.

Develop and experiment an on-the-job training platform for ultrasonographists for pregnancy surveillance to improve early detection of foetal malformation.

Develop, implement and validate a multi-level model for moving abdominal organs for use with Focussed Ultra Sound (FUS) and Magnetic resonance-guided focused ultrasound surgery.

Provide a means to seamlessly integrate the available multi-modal images and the patient information on a single clinical workstation.

Model and simulate the MAP kinase pathway to understand its role in the development to cancers

Provide methodology, tools and contribution to standards used in the development of real time embedded systems.

Network to stimulate an active debate amongst a key group of experts on the research taking place for surface transport.

Provide guidance and assistance in preparing and improving the business plans of TEN-Telecom funded projects.

Provide an order of magnitude increase in the capacity density of beyond next generation mobile wireless networks.

Introduce a disruptive methodology for the design of complex critical applications allowing safety and time criticality aspects composition, taking into account disturbances as elements of the problem space, identifying analysis methods and techniques supporting this new approach and demonstrate the applicability of these techniques through meaningful examples of complex control functions.

Improve in the flow of information acquired by moving vehicles and in its quality and reliability, thereby enhancing road efficiency and traffic safety on urban, intercity arterials and rural roads.

Provide high-quality support to the PROMETEUS education and training community, facilite the activities of the PROMETEUS Signatories, Steering Committee and Special Interest Groups in achieving the aims and objectives of the PROMETEUS Memorandum of Understanding

Deliver a new discrete electron device which can be potentially used to develop very high-speed (?10GS/s), low-power (?1?W), high-resolution (? 5 bits), analog-to-digital converters (ADCs) to answer the demand in industrial sectors of telecommunications and radar systems

Exploit the unique physical properties of NV color centres in ultrapure single-crystal CVD-grown diamond to develop innovative devices with unprecedented performances for ICT applications.

Design, implement and test - in a large-scale experiment - an environment for collaborative learning (CL) through electronic discussion

El-Peacetolero’s overarching ambition is to design a TRL 7 hand-held, low power, embedded optoelectronic system that can deploy AI for in-situ real-time measurement, identification and diagnosis of the material state of aging polymers in an industrial environment.

The objective of Enhanced Learning Unlimited (ELU) is to look on how interactive digital TV can be used to increase learning opportunities in the home, office and school.

Demonstrate an Internet-based service, providing easy and multilingual access to databases of trademarks and industrial designs. These databases are populated and maintained by European IP Offices and SMEs.

Set-up a natural language access in French, English, Spanish and German to patent databases, especially for non-professional users, and to develop a sustainable service.

ePerSpace project aims at significantly increasing the user acceptance of networked audiovisual systems and applications at home and virtually anywhere by developing innovative personalised value-added networked services.

Support the collaborative action initiated in the eEurope Smart Card Charter Trailblazer 1 Public Identity.

A three-year project aiming at the mass market adoption of advanced audiovisual networked services, at home and everywhere. Feel@Home will develop an integrated open architecture and business proposals to enable an increasingly proactive participation of residential users in the usage of ICT.

Develop and validate new distant learning services for user groups who need access to education and training outside formal education settings

Demonstration of a federated identity management (IDM) corresponding to the Liberty Alliance concepts

Realize the vision of a "democratic" grid as an ubiquitous platform where individuals, associations and small businesses can recover resources from the Internet without having to invest and manage computing resources.

Development of a virtual copier, i.e. an innovative end-to-end service solution for seamless, secure and fast communication of high-quality colour documents over open networks (fix and mobile).

Establishment and evaluation of secure transactional platform with value-added on-line (telephone and Internet) and in stores services in a European context.

Develop an intelligent cognitive-based open learning system and environment, adapted to individual learners' needs and ensure their take-up in the education sector at a European level.

INSPIRED will develop the second generation called Trusted Personal Device to provide Trust and Security to users and on-line services in the future ambient intelligence and ubiquitous computing environments.

Development and evaluation of a miniaturised videoprobe system including a micro-electronic image sensor, wireless data transfer, post- processing and display as well as micro-mechanical components and localisation capabilities.

Develop a RF ID tag system with multi-read capability and very small read/write RF tags. Computer simulation was be used to optimise RF system design, to predict reading performance, support compliance with RF regulations and facilitate adaptation of LAUREL to various applications.

Raising the awareness of potential users of the solutions developed, by connecting technology suppliers with those who will deploy it and by identifying and exploiting synergies within the cluster.

Address the needs of today's information and communication society regarding language technologies creating an increasing need for new standards as well as urgent recognition of existing de facto standards.

Develop new concepts and techniques to allow fast and natural access to multimedia databases.

Develop an intelligent, robust and affordable solid state microsystem enabling fast and parallel acquisition of 3D-information.

Develop a global solution based on a modular SOC platform providing the disruptive technology of embedded dynamically reconfigurable computing completed by a software (SW) oriented design flow.

Design and evaluate a large-scale demonstrator, for proving the feasibility and performance of multi-beam receiving antennae.

Provide multilingual summarisation to facilitate access to information retrieval systems and in particular access to the content of electronic documents over the Internet.

Develop a new imaging head that will increase the speed, decrease cost and improve the ease of maintenance of Karat Digital Press's new digital offset press, the 74 Karat.

Focus on optimizing the bandwidth of IPTV for the delivery of multiple HD streams over a single ADSL line, and by that enabling multiple HD channels per household.

Specify, develop and demonstrate a flexible and scalable architecture for large-scale interactive multi-participant applications on the Internet and to contribute to standards in this field.

Build a high quality video content distribution solution for TV channels and telecom operators on ADSL broadband networks.

Assess, in a global way, the technology priorities and R&D orientations of the smart card industry.

Provide a novel way of using the acquired knowledge to improve organisational procedures.

Offer high speed Internet and multicast services for info kiosks at frequently attended places deploying a return channel satellite system.

Increase the common technical basis and interoperability of smart card based systems and services, and ensure the easier deployment of smart cards in a wide range of applications.

Develop a system level design and verification platform for hardware and software integrated systems

Develop and validate a modular and interoperable teletraining platform that will address the needs of training centres, of users and of instigators of training programmes

Reduce the ?time to performance? of Europe?s labour force through the optimisation of knowledge creation, delivery and acquisition facilitated by ICT

Develop a complete end-to-end framework solution, consisting of hardware and software focussing on interoperability, use of open standards, and protection of intellectual assets.

Resolve the current privacy concerns regarding the use of fingerprint biometrics for ID management.

Design and implementation of a test-bed for new applications based on UWB technology, including high quality video and broadband multimedia services.

HydroZONES represents an interdisciplinary consortium that adopts a strategy to regenerate articular cartilage based on biofunctional hydrogel-based implants that mimic the tissues zonal structure and function. The defined endpoint of HydroZONES is the positive long-term pre-clinical evaluation of at least one construct, according to pre-clinical regulatory requirements and in GMP standards. The second major aim of HydroZONES is the development of a predictive 3D in vitro assay for chondral implants, validated against our in vivo results, together with the hardware to perform the assay.

The AIMS-2-TRIALS vision is to apply a precision medicine approach to ASD and improve patient outcomes by tailoring treatments to a patient’s biological profile.

Identification of novel critical genes and define their role in angiogenesis.

Develop innovative drugs against influenza virus infections based on a novel concept that precludes the development of viral resistance and ensures efficacy against upcoming pandemic influenza strains.

ASTERIQS will exploit quantum sensing based on the NV centre in ultrapure diamond to bring solutions to societal and economical needs for which no solution exists yet.

Blood-based biomarkers, such as circulating tumor cells, circulating free tumor DNA and other tumor cell derivatives like micro RNAs, are potential indicators for the development of a tumor. Derivation of these markers from blood – so called “liquid biopsy” – may offer an additional invaluable tool for modern cancer therapy. The Public-Private-Partnership CANCER-ID with currently 39 partners from 14 countries aims at the establishment of standard protocols for and clinical validation of blood-based biomarkers. It brings together experts from academic and clinical research, innovative Small-to-Medium sized Enterprises (SMEs), diagnostics companies and the pharmaceutical industry thus providing a unique setting for establishing clinical utility of liquid biopsies.

Several neurodevelopmental disorders often occur together and, further, are associated with other somatic illnesses. This combination significantly affects a person's length and quality of life and there are no effective treatments. CANDY is following a trail of rare genetic variants that are shared in many neurodevelopmental disorders and the possibility that immune dysregulation at some point plays a role. Insight could point to personalised treatment and a drastic reduction in suffering for affected patients.

The EU-funded project CARAMBA is using the revolutionary CAR-T cell technology to tackle multiple myeloma, a rare hematological disease. Within CARAMBA, a phase I/II clinical trial of immunotherapy will be conducted with patient-derived T-cells that are engineered to express a synthetic chimeric antigen receptor (CAR) specific for the myeloma antigen SLAMF7.

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 patients, which will be used for better characterization of TBI and for Comparative Effectiveness Research (CER).

Provide the appropriate structuring and coordination of a cluster of six research projects working on the topic of replacement of current repeated dose systemic toxicity testing in human safety assessment. The cluster covers phase I of the long-term research initiative SEURAT (?Safety Evaluation Ultimately Replacing Animal Testing?).

Discover colon cancer (CRC) and breast cancer (BC) biomarkers for patient follow-up (monitoring markers) by exploiting the capacity of 3 state-of-the-art high-throughput technologies in an integrated systems biology approach.

Modelling and predicting sensitivity to targeted therapies in colorectal cancers

Gathered resources and knowledge in the understanding, diagnosis and clinical management of connective tissue cancers, also opening new therapeutic options.

The EU-funded CRUCIAL project intends to identify the role of microvascular rarefaction in cognitive impairment and heart failure by developing innovative imaging instruments and taking advantage of non-contrast and AI methods.

Develop tools and optimised procedures to enable cryopreservation of different stem cell types and allow safe production of sufficient numbers of high-quality cells for future human therapy.

CULPRIT-SHOCK is expected to clarify the role of different percutaneous revascularization strategies in patients with cardiogenic shock secondary to myocardial infarction and multivessel disease.

Set up a screening pipeline of high content, high throughput as well as classical functional and "-omics" technologies to identify and investigate human biomarkers in cellular models for repeated dose in vitro testing.

Develop of automated handling processes for pluripotent cells (e.g. hiPSCs) with integrated readout methods, required for the use of pluripotent cells in high-throughput and high-content assays

The multidisciplinary European consortium dsd-LIFE wanted to evaluate and improve the treatment and care in the different conditions in close cooperation with patient organisations. The project is unique in that it investigates issues which are not only relevant for care but also for empowerment of people with DSD

Establish a centralised, not-for-profit bank for induced pluripotent stem cells (iPSCs). EBiSC will meet the pressing demand for access to a diverse collection of quality-controlled, disease-relevant iPSC lines.

EBiSC2 builds on the achievements of the European Bank for iPSCs (EBiSC1) in centralising existing capacities across Europe in a unique banking and distribution infrastructure for research use in response to the increasing demand for human induced pluripotent stem cells (iPSC).

The objective of the Emerald Project is to improve mental health outcomes by enhancing health system performance. Specifically, the Emerald Project aims to identify key health system barriers to, and solutions for, the scaled-up delivery of mental health services in low- and middle-income countries (LAMICs), and by doing so improve mental health outcomes in a fair and efficient way.

Develop relevant imaging tools will lead to a better understanding of how cell therapy works, the possibility of response monitoring in patients, and sufficient safety of the treatment.

The EpimiRNA consortium represents a major interdisciplinary effort to apply the breakthroughs of microRNA research to the problem of epilepsy, with epilepsy researchers, geneticists and biochemists, clinicians and research-active companies working together to understand microRNA mechanisms in epilepsy patients. EpimiRNA’s goals are (1) to explain how microRNAs and their protein targets contribute to the development of epilepsy and triggering of seizures; (2) to identify genetic variation in microRNAs in epilepsy patients; (3) to test microRNA-based drugs as potential future therapeutics; (4) to develop microRNAs as biomarkers to track, treat and prevent epilepsy.

In order to someday be able to prevent the development of epilepsy, the multidisciplinary research project EPITARGET is focused on the process leading to epilepsy (epileptogenesis) in adults. The main hypothesis is that there are combinations of various causes, acting in parallel and/or in succession, that lead to epileptogenesis and the development of seizures. The central premise and vision is that by using a combinatorial approach to identify appropriate biomarkers that allow the prediction of the disease and by developing effective anti-epileptogenic therapeutics, patients at risk can be treated before they even have epilepsy.

Develop a novel toxicity test platform based on embryonic stem cells (ESC), especially human ESC (hESC), to accelerate drug development, reduce R&D costs and propose a powerful alternative to animal tests (3 Rs).

European Autism Interventions - A Multicentre Study for Developing New Medications (EU-AIMS) - is the largest single grant for autism in the world, and the largest for the study of any mental health disorder in Europe. EU-AIMS involves a novel collaboration between organisations representing affected individuals and their famillies (Autism Speaks), academia and industry who, for the first time in the world, have come together to develop the infrastructure underpinning new treatments for autism.

In a large (30 Million €) H2020-supported collaborative project, academia joins forces with small and medium-sized enterprises (SMEs), large industry, contract research organisations (CROs) and regulatory bodies to achieve a paradigm shift in toxicology towards a more efficient and animal-free chemical safety assessment.

The ultimate goal of EURE-CART is to bring EU at the forefront CAR T-cell immunotherapy. In this Project, we will extend the applicability of CAR T-cell immunotherapy to incurable tumours that have never been tackled with this approach.

FemNAT-CD is a new European project that aims to understand the causes of sex differences in behaviour. The project will study similarities and differences between boys and girls in brain structure and function, hormone levels, genetics, emotion recognition and regulation, and physiological activity.

Test a Fixed-Dose-Combination pill for cardiovascular prevention and treatment in populations with diverse socio-economic characteristics.

Improve our understanding of cellular self-renewal and differentiation processes into tissue-specific cells.

The innovative idea behind HemAcure: The isolation of endothelial cells from peripheral blood of haemophilia A patients and FVIII gene correction of those cells.

The Corona-virus outbreak is continuing to spread. By beginning of February, the number of infected people surpasses 42,000 infections, and the death toll continues to rise. As authorities and responders are struggling to contain the spread, news about mass quarantine camps or shortages of personal protective equipment threaten the health systems globally, fueled by rumors and mis-information. The disruptions of (medical) supply chains, the lack of capacity to treat patients and the spread of rumours fuel an atmosphere of uncertainty and mistrust, hampering an effective response. While traditional models of disease outbreaks largely focus on infection rates, new methods are needed to integrate behaviour from the bottom up, and integrated in macro-level models to coordinate the response world-wide.

The HYPERDIAMOND project will develop and commercialise two platforms for hyperpolarized, MRI-based molecular imaging, by leveraging revolutionary progress in quantum- and nano-technology.

Development of new and improved culture methods, media and protocols for stem cell cultivation and differentiation.

The European collaborative project HypOrth aims to develop hypoallergenic material for endoprotheses, pursuing two major goals: HypOrth intends to improve the understanding and diagnosis of complications associated with an implant, primarily focussing on adverse immune reaction and infection. Based on these insights the project will develop innovative approaches for renewals in orthopaedic arthroplasty with improved biocompatibility.

Better understanding of (1) the molecular and cellular circuits involved in the development of cancers caused by these infectious agents, (2) the mechanisms of long-term persistence of these infectious agents in apparently healthy hosts, and (3) which genetic factors contribute to cancer development

Address the complex issues associated with the future of biomedical research in the EU, and addresses ways of achieving accelerated development of safe and more effective medicines, aiming to revitalize the European biopharmaceutical research environment.

The European collaborative project LENA aims to develop a safe, effective medication for patients with serious heart conditions – the ACE inhibitor Enalapril – in a new formulation for children and infants. This drug has originally been developed for adults and is already widely used successfully as a so-called “off-label” drug in children without paediatric license. To date, no child-friendly formulation exists.

Perform functional studies to understand the dissemination and outgrowth of metastasis through systematic analysis of the Core Invasive Machinery contained within integrin-mediated ECM attachment structure.

Develop new simple to use diagnostic tests as well as new, nanobody based, treatment methods for trypanosomiasis involving the African research community.

Understand how NOX controls neuroinflammation, identify novel molecular pathways and oxidative biomarkers involved in NOX-dependent neuroinflammation, and develop specific therapies based on NOX modulation.

The ambition of PHAGO is to improve patient outcomes through improved understanding of the biology of TREM2 and CD33 and their biological networks and pathways, and develop consequent therapies aimed at phagocyte dysfunction in AD. We expect to achieve this goal by means of modulating microglia/macrophage activation through TREM2, CD33 and related signalling pathways, and determine the effects of such modulation on microglia/macrophage function, Aβ and neurodegeneration.

PRECIOUS is a pragmatic, randomised, open clinical trial with blinded outcome assessment in 3800 patients with acute stroke aged 66 years or older. The trial will assess whether pharmacological prevention of infections and fever, and early management of dysphagia, will reduce the risk of death, poor functional outcome, and poor quality of life, and lead to reductions in the costs of stroke care throughout Europe.

A main goal of PRONIA is to secure its intellectual property rights with the help of key investors in the field and transform into a European company to commercially exploit these prognostic services through internet-based telemedicine applications.

Combine 5 international clinical studies, all supported by highly innovative microbiology, mathematical modelling and data-management, to determine the efficacy and effectiveness of cutting-edge interventions to reduce carriage, infection and spread of Multi-Drug Resistant Gram-negative Bacteria (MDR-GNB).

In order to better understand the common mechanisms of chronic autoimmune diseases, such as rheumatoid arthritis and vasculitis, the RELENT project will analyse data from a variety of measurements (clinical, serological, genetic, transcriptome) and thus develop new bio-markers for these diseases. These should allow the tailoring of the most efficacious treatment to each patient with a chronic autoimmune disease.

Exploit the vast potential of RNA interference (RNAi) for human therapy, based on an advanced understanding of the underlying mechanisms

Science and society are increasingly demanding a paradigm shift towards chemical safety and risk assessment without using animals. The project will develop, validate and implement integrated approaches to lead the way towards next-generation risk assessment (NGRA). Innovative mechanism-based new approach methods (NAMs) will exclusively be in vitro and in silico and relevant for human health. Through systematic and iterative evaluation of its NAM toolbox, the project will optimize a strategy to assess chemical exposure, toxicokinetics, and toxicodynamics. RISK-HUNT3R will provide a full sustainable framework for NGRA that is human-relevant, fully based on non-animal approaches, and fit for implementation through engagement with chemical safety regulators.

Study the impact of antibiotic exposure on AMR with a multidisciplinary approach that bridges molecular, epidemiological, clinical and pharmacological research.

SCREENED will develop 3 different three-dimensional (3D) in vitro assays based on rodent and human thyroid cell constructs. The 3D assays will be used to screen the effect of endocrine disruptors (EDs) on the thyroid function in a unique biological sex-specific approach.

Address the call set forth by H2020 PHC17, by comparing the effectiveness of a polypill strategy to the existing usual care in reducing major adverse cardiovascular events (MACE): cardiovascular (CV) death, recurrence of acute myocardial infarction (AMI), stroke and revascularization, in secondary prevention in the elderly.

The main purpose of the project is to develop a highly-powered and efficient software engine (SENATOR). SENATOR will be capable of individually screening the clinical status and pharmacological and non- pharmacological therapy of older people with multi-morbidity in order to define optimal drug therapy, highlight ADR risk, indicate best value drug brand for selection and provide advice on appropriate non-pharmacological therapy.

Seven in ten Europeans over the age of 65 live with sight or hearing problems and over two-thirds live with depression or dementia. When combined together, the cumulative impact of such dual or triple impairments is far greater than that of the individual conditions alone. The scale of combined sensory and cognitive problems is substantial but, as yet, poorly understood. SENSE-Cog aims to investigate this combined impact on patients, and to develop new tools and at-home support that could improve quality of life and help optimise health and social care budgets and resource allocation across Europe.

Due to lack of targeted interventions, compliance issues, insufficient effect sizes and a high non-responder rate to currently available interventions, there is an urgent need to develop innovative and new interventions for chronic paediatric neuropsychiatric disorders, such as Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD). Transcranial direct current stimulation (tDCS) has been shown to be an innovative, effective and safe alternative treatment approach for neuropsychiatric disorders in adults. Here, for the first time, the effect of tDCS on core neurocognitive and behavioral outcomes will be proven in children and adolescents.

The ambition of SVDs@target is to identify key mechanisms common to multiple SVDs and to validate novel mechanisms through interventions, with the ultimate goal of reducing the burden of SVDs, stroke and dementia.

SysmedIBD brings specialists from Europe, Israel and New Zealand and is centrally coordinated by Prof. Werner Müller at Manchester University. The main objective of SysmedIBD is to better understand chronic Inflammatory Bowel Disease and to find new approaches for therapies.

The main objectives of T-Control are the clinical development of two Streptamer-based cell selection processes and their corresponding cell products. The different cellular products will be a multi virus- and a tumor-specific T cell product, to boost immune function post-transplant for the treatment of infections and residual/recurrent tumor cells after HSCT. In addition, a primary regulatory T-cell product will be developed to suppress the immune function post-transplant for the treatment of GvHD after HSCT.

The TargetHerpes consortium will create innovative opportunities for the application of the novel tech-nologies of three SMEs in the development of a new generation of antiherpesvirus treatments

Integrate the European efforts towards the development of novel tuberculosis vaccine candidates and forward these vaccines to small scale, Phase I human clinical trials in Europe and in Africa.

Assuming an annual birth rate of 10.25 births/1,000 population approximately 25,000 Extremely Low Gestational Age Newborns are born every year in the EU. However, no uniform criteria exist to define hypotension and the evidence to support our current management strategies is limited. The HIP Trial have assembled a consortium with expertise in key areas of neonatal cardiology, neonatology, neurophysiology, basic science and pharmacology with the intention of answering these questions.

More than three percent of the world's population (about 260 million humans) are chronically infected with the hepatitis B virus (HBV). Worldwide 880,000 humans die each year from the sequelae: liver cirrhosis and hepatocellular carcinoma. Currently, there is no cure. The therapeutic vaccine TherVacB aims to cure patients with chronic hepatitis B. A consortium of leading virologists, immunologists and specialized physicians will use a newly designed vaccine as an immunotherapy in a two-year clinical trial starting in 2021. With three vaccine shots, one every four weeks, the vaccine induces neutralizing antibodies and T-cell responses. At first, two protein antigens are injected, followed by an MVA (“modified vaccinia virus Ankara”) vector. This vector is designed to express hepatitis B viruses found worldwide. Since Africa suffers from a high infection rate and particular HBV viruses can be found there, part of the clinical trial will be conducted in Tanzania. This shall also help building local capacities for diagnosing and treating hepatitis B.

The VIROFIGHT consortium proposes a radically new approach to fight viral infections, to help reduce the scale and sheer impact of viral infections, to address the problem of a lack of broadly applicable antiviral treatments, and to create means for combating emerging pathogens.

The European Lead Factory is a 196 Mio € collaborative public-private partnership funded by IMI-JU, aiming to deliver innovative drug discovery starting points. Having established the first European Compound Library and the first European Screening Centre, the EU Lead Factory gives free access to up to 500,000 novel compounds, a unique industry-standard uHTS platform, and much more.

iTRACK is designed to be a cost effective open source system, supporting organisations where resources may be limited. To further facilitate its uptake by humanitarian organisations operating conflict and disaster missions, we design technology and policies in with humanitarian practitioners with pilot applications with the World Food Programme and iMMAP in on-going conflict disasters in the Middle East.

Efficient NII (non-intrusive inspection) of containerised freight is critical to trade and society. Freight containers are potential means for smuggling (e.g. tobacco), illegal immigration, trafficking of drugs, mis-declared goods and dangerous illicit substances, including explosives, nuclear material, chemical and biological warfare agents and radioactively contaminated goods. One inspection NII technology cannot cope with all these targets. The C-BORD Toolbox and Framework will address all these targets and enable customs to deploy comprehensive cost-effective container NII solutions to potentially protect all EU sea- and land-borders, satisfying a large range of container NII needs. The C-BORD Toolbox will include 5 complementary innovative detection technologies: delivering improved X-rays, Target Neutron Interrogation, Photofission, Sniffing and Passive Detection. User interfaces and data will be integrated to optimise effectiveness and efficiency of end-users and systems. The C-BORD Framework will help customs analyse their needs, design integrated solutions, and optimise the container inspection chain; it will address detection levels, false alarm levels, throughput, health & safety, logistics and cost & benefits. C-BORD will increase the probability of finding illicit or dangerous content with at least equal throughput of containers per time unit, reduce the need for costly, time-consuming and dangerous manual container inspections by customs officials, and in case a container is opened, increase the probability of finding illicit materials. C-BORD involves stakeholders from 8 EU countries, as partners (5) and advisory group members (3). On 3 custom sites integrated solutions will be trialled, respectively addressing the needs of big seaports, small seaports and mobile landborders. To optimise sustainable impact, C-BORD will actively engage with a large community, will support policy implementation, evolution and start early exploitation planning.

To develop a comprehensive Open Toolbox for dealing with CBRN crises due to terrorist attacks using non-conventional weapons or on facilities with CBRN material.

The CURSOR proposal aims at developing new and innovative ways of detecting victims under debris. This includes the coordinated use of miniaturized robotic equipment and advanced sensors for achieving significant improvements in search and rescue operations with respect to (a) the time used to detect trapped victims after a building structure has collapsed, and (b) an informed and accelerated decision making by first responders during rescue operations allowing for the deployment of expert personnel and, in particular for operations in hazardous environments, suitable equipment at prioritized locations.

The DAREnet project is to support flood management practitioners across the EU Danube River region and from different disciplines to deepen and broaden their Research, Development and Innovation related collaboration (=RDI). DAREnet will build a multi-disciplinary community of practitioners, operating in a network of civil protection organisations, and supported by a broad range of stakeholders from policy, industry and research. Together they will build a transnational and interdisciplinary ecosystem to foster synergies, innovation and its uptake.

DRIVER focuses on augmenting rather than replacing existing capabilities and will aim at producing a comprehensive, well-balanced and cost-effective Portfolio of CM tools exploiting high potential RTD work from the last decade. This portfolio will address not only needs of professional responders but also of society at large. DRIVER will carry out experimentation campaigns in three strands: tools and methods for responders, resilience of civil society and learning by both. The intra-strand experimentation leads into two Joint Experiment campaigns and a Final Demo focusing on challenges requiring highly complex interaction between CM tools. To evaluate and benchmark these CM tools, a strong evidence base for tool selection is crucial; to this end DRIVER will build a distributed European CM Test-bed, itself a major innovation. To maximise impact beyond the scope of the project and of the DRIVER consortium it is necessary to develop the sustainability of the European Test-bed, the exploitation of the DRIVER Portfolio of Tools and to make emerge a European CM community, which shares a common CM understanding and is increasingly willing to share capabilities and collaborate in CM innovation.

The mission of ENTRANCE is to develop and validate a comprehensive user-based ENTRANCE Toolbox for risk-based non-intrusive inspection (NII) of cross-border freight movements, with particular focus on the EU Customs Union border.

FIDELITY is a multi-disciplinary initiative which will analyse shortcomings and vulnerabilities in the whole ePassports life cycle and develop technical solutions and recommendations to overcome them

Develop an innovative, Optical Intruder Sensing and Authentication technologies that will dramatically improve the Cost/Performance ratio of security systems, thus becoming an enabler for the widespread availability of reliable and affordable security, leading to more infrastructures being protected.

Set up and develop a sustainable network of Law Enforcement Agency (LEA) practitioner organisations from all over Europe. The mission of this network will be to stimulate LEA capabilities to influence, develop and take up research, development and innovation (RDI) that is useful and usable for LEAs, and thereby help them to tackle the major challenges they face.

Though difficult to quantify, the variety of possible ID document frauds at borders is a reality that threatens politicians holding responsibility for borders as well as EU citizens. Based on the needs expressed by practitioners, the iMARS consortium has shaped a project that will improve the operational capacity of passport application and border control operators and ensure the uptake of its outcomes after the project’s end.

Research and develop novel technologies for personal digital support systems as part of an integral, secure emergency management system to support First Responders in crises occurring in various types of Critical Infrastructures under all circumstances.

iProcureNet aims to create an ecosystem of procurers, prescribers, legal advisors and other key stakeholders of security procurement, to • share and analyse procurement trends and needs; • develop common and standardised practices from the technical, legal and financial perspectives, and • open pathways for joint procurement.

Pan-European Network of Customs Practitioners (PEN-CP) project builds a network between distinct customs administrations to create an ecosystem for interoperability, knowledge sharing and innovation to improve European security though more efficient control of the illicit trade flows.

Develop a standard interoperable solution to secure access to airports and aircrafts. Promote the early adoption of biometrics and smart cards as part of a global system to streamline the passenger process within an airport until the ultimate boarding phase.

Develop an affordable global generic solution for the detection and management of drinking water crises resulting from CBRN contamination.

Handling the crises faced by modern societies often requires the coordination of multiple types of stakeholders from different countries. One of the key requirements to manage crisis is to have access to situational awareness (SA). However, current SA solutions (SAS) are not adapted to operate in cross-border contexts and present several shortcomings related to interoperability, data management/processing, decision making, standardisation and procurement. This hinders a reliable sharing of SA information. SAYSO will address these shortcomings and pave the way for the development of innovative European cost-effective Multi-Stakeholders SA Systems (MSSAS) which will provide practitioners with user-friendly solutions, providing a clear picture of the situation at hand with relevant advices.

Build an innovative comprehensive toolbox of devices and best-of-breed technologies for the enhanced detection and identification of difficult to detect radioactive sources and nuclear material

Transfer traces analysis currently suffers from several limitations: highly subjective and selective, this process is also very time-consuming, hence inefficient, whereas results are difficult, if not impossible, to compare and share among forensic laboratories. As a consequence, the use of forensic data in cross-border investigations, and in foreign courts is limited. Creating a unified transfer traces automated analysis toolkit would allow for a higher productivity of forensic workers, better crime resolution and enable further collaboration across end-users.

Develop solutions to a range of problems related to border security, basically aiming to complement dogs and leverage their capabilities. SNIFFER also aims at fine-tuning a range of highly promising technologies for olfactory applications in view of satisfying the stringent user requirements related to "artificial sniffers"

The aim of the SOURCE Network of Excellence is to create a robust and sustainable virtual centre of excellence capable of exploring and advancing societal issues in security research and development. The SOURCE Network of Excellence is built upon five types of activities: networking activities, research, information gathering, education and training, and knowledge-sharing. These five areas together address both the ambitions and the expected impact of the Work Programme specific to the Security call. Through an integrated information gathering hub, education programmes across the security sectors, and a comprehensive programme of networking activities the SOURCE project will advance European excellence in research and industrial innovation and form the foundation for a permanent virtual centre of excellence capable of continuing to bring added-value to research on societal security. Through a broad set of concerted activities the centre will gather experts and actors from all levels of the security chain (researchers, industry actors, policy-makers, civil society, end-users and the public at large), all linked by a common project of documenting, analysing and understanding the link between security and the society in which it is played out. Through an array of networking activities, meetings, scientific and popular publications, film, press and social media, a scholarly journal and the formation of an international association for the study and improvement of societal security, the SOURCE Network of Excellence will meet the goals of raising the awareness among policy makers and end-users, raising the competitiveness of the security industry by better applying it to the social layers of insecurity in society and, as a consequence, contribute to the improvement of the well-being and security of European citizens.

Develop, trial and assess a comprehensive open distributed pan-European Platform for serious gaming leveraging state-of-the-art decision support tools, for the training and competence assessment of Security Critical Agents (SCA).

Video recordings have become a major resource for legal investigations. Since no mature video investigation tools are available and trusted by LEAs, investigators still need to carry out the analysis of videos almost exclusively manually. Current practices are too resource intensive to handle the yet huge and steadily increasing volume of videos that need to be analysed after crimes and terrorist acts. The consequence is that LEAs cannot analyse all available videos because of the huge effort needed, and the extraction of first clues from videos after a terrorist attack takes more time. VICTORIA will address this need and deliver a Video Analysis Platform (VAP) that will accelerate video analysis tasks by a factor of 15 to 100 (depending on the use case), while providing very reliable results.

Provide a micro- and nano-scale based manufacturing and functionalisation technology for the generation of fully vascularised bioartificial tissue that enables entire nutrition and metabolism. The bioartificial vascularised skin engineered in ArtiVasc 3D will, for the first time, allow tissue replacement with optimum properties.

Integration of innovative process equipment to attain radical performance enhancement for whole process, thereby contributing to significant improvement in supply?chain sustainability for the chemical industry.

Improve the management of emerging risks, related to ?new technologies? in European industry. This is being achieved by building new management paradigm for emerging risks as a set of principles supported by a common language, agreed tools & methods, and Key Performance Indicators (KPI), all integrated into a single framework.

The PACIFIC consortium will develop a new, low-cost and environmentally friendly tool for exploring for mineral deposits beneath the surface. The approach will build on the ""traditional"" passive seismic method, which is capable of providing useful broad-brush background information about the geological and structural setting of mineralised regions, but lacks the resolution needed for reliable identification of ore bodies.

Break new paths for the laser beam processing of advanced polymeric materials exploiting the benefits of new high brilliance laser sources and to challenge the limits of conventional joining processes as well as existing production systems and equipment.

Facilitate and accelerate the transfer of innovative laser technology from the laboratory to industrial applications and to disseminate information and best practices, promoting the use of laser equipment and expanding results to additional application sectors.

Flexturbine will strongly advance state-of-the-art fossil fuel power plant engine technology to allow flexible high load changes as the fundamental necessity to sustainably and successfully establish renewable energy sources in the European power grid in a medium-term perspective: - Stability of the energy grid without variations - Flexibility for a fast ramp-up and strongly cyclic operation of power plants - Efficiency by minimising and reducing CO2, NOx, and other greenhouse gases, and the cost and affordability of electricity

The HYCARUS project will design a generic PEM fuel cell system compatible of two NEA, develop, test and demonstrate at TRL6 one of the two (Galleys, lavatory) for a single aisle aircraft. A secondary electrical power generation model for a business executive jet will be run. The application will be tested with the fuel cell system and the storage system under flying conditions. Furthermore, investigations will be made to understand how to capture and reuse the by-products.

Hydrothermal liquefaction (HTL) is emerging as innovative technology to produce renewable transportation fuels. The advantages of HTL are reflected in its high feedstock versatility, its ability to convert wet materials and its advantageous environmental and economic performance. Bio-crude, the primary HTL product, can be upgraded to high-quality fuels. The objectives of HyFlexFuel include: 1) Demonstrating HTL conversion compatibility with diverse advanced biomass feedstock…

The EU-funded HYFLEXPOWER project will develop and operate the first fully integrated power-to-hydrogen-to-power industrial scale power plant, including an advanced dry-low emissions hydrogen gas turbine. The already installed SGT-400 gas turbine package will be upgraded with the ultimate goal to produce 12 MW electrical energy using fuel mixtures that contain up to 100 % hydrogen.

INNO4GRAPH aims at developing a set of physical and digital tools and methods to be used both upstream of dismantling operations (for material characterisation and decision-making) and during dismantling operations (for handling and cutting).

Define technological and operational means for maximising flexibility provision to the electricity network. It will identify the regulatory framework to bring such flexibility service to the energy markets and will provide enhanced market designs and related business mechanisms.

NEXUS will develop and demonstrate novel, beyond state of the art, specialised vessel and logistics for safe and sustainable servicing of offshore wind farms. NEXUS includes: simulation, model testing, consideration of the most suitable construction and production principles for small series or one off vessels of this type. Key aspects of NEXUS include environmental impact assessment, cost estimation as well as both the marketability (technology push), and the cost effectiveness of the offshore operations concerned (demand pull). The project will develop the concepts and validate on a demonstrator at a technology readiness level (TRL) 5 with the overall aim of reducing cradle to grave costs by at least 20% compared to current practices. In addition NEXUS will enable the increase the professional skills of workers and the capability of European industry and in particular SMEs within the marine and maritime sectors to develop and commercialise specialised vessels and related technology, and will support European growth and employment through development of a blue economy.

PASTELS aims to significantly increase the knowledge within Europe of innovative passive systems, namely SACOs and CWCs, and the ability of several European system and CFD computational codes to be able to accurately model key phenomena such as natural circulation loops and condensation.

The ambition of SUN-to-LIQUID is to advance solar fuels well beyond the state of the art and to guide the further scale-up towards a reliable basis for competitive industrial exploitation. Large-scale solar fuel production is expected to have a major impact on a sustainable future transportation sector.

Retrofitting critical parts of thermal power plants which have already seen experimental proof-of-concept and are expected to significantly contribute to flexible operation. The technologies will reduce the minimum load, increase the ramp rates and reduce the costs per cycle.

Support the widespread adoption in Europe of innovative methods of science teaching and provide extensive teacher training on inquiry-based methods.

STEP-IN will develop a global methodology for the effective analysis and tackling of energy poverty. The ICT tools provided by STEP-IN will support consumers, advisors and local stakeholder organisations to make effective decisions.

Develop cost-effective and reliable tools for the co-existence and traceability of GM, conventional and organic crops.

Include an exposure assessment of humans from animal/environmental sources. The ecological studies on isolates will be verified by in vitro and in vivo studies. Moreover, real-life intervention studies will be conducted aiming at reducing the use of antimicrobials in veterinary practice.

ADVISE aims to enhance – and in some cases – to enable for the first time the ultrasonic inspection of complex structured materials, for which conventional ultrasonic techniques suffer from severe performance limitations due to the micro and/or macro-structure, in order to improve confidence in and reliability of the inspection of Generation II and III reactors.

Improve 3D nuclear medical imaging technologies significantly: reduction of radiation exposure, increase of spatial and temporal resolution.

The main aim of the sCO2-4-NPP is to bring an innovative technology based on supercritical CO2 (sCO2) for heat removal in nuclear power plants (NPPs) closer to the market.

Safe Long-Term operation of light water reactors based on improved understanding of radiation effects in nuclear structural materials.

TeaM Cables will develop a novel multiscale approach for more precise estimation of the cable lifetime. The project will analyse the effects of irradiation and temperatures on cables from micro- to macroscale level, in order to develop multiscale models of ageing. Ageing in normal operation conditions and accidental conditions will be addressed. The unique multi-scale and kinetic models produced by the project will be integrated into an open access tool – the TeaM Cables tool - which will be built on the merger of a currently used European cable management tool with a cable ageing modelling tool. In parallel, criteria and protocols for on-site use of non-destructive testing techniques will be proposed. The TeaM Cables multiscale modelling approach and associated tools will allow NPP operators to safely extend the plant life duration of generation II and III reactors and thus contribute to the production of sustainable energy responding to future energy needs.

Research, innovate, architect, design, develop and validate a Non-Dependent High-Performance ManyCore Rad-Hard Processor and DSP Computer for Computation-Intensive Space Applications

Enable dramatic reductions of delay in the delivery of Earth Observation (EO) Hyperspectral (HS) data from image capture to receipt by the end-user of end product on the ground, from days or weeks to real-time or near-real-time which represents an improvement factor of 100x in delay and 420x in effective bandwidth.

Satellite Swarm Sensor Network (S3NET) is a 2.5-year H2020 project coordinated by iTUBS that started 1st May 2016. Its consortium gathers 8 partners from 4 countries for a global budget of 2.5M€. In the field of Earth observation from space modern approaches show a trend of moving away from the classical single satellite missions, towards fractionated and distributed sensor missions, where multiple satellites possibly carrying different types of sensors act in a formation or “swarm”. Such missions promise an increase of imaging and service quality and in many cases a decrease of deployment costs for satellites that can become smaller and less complex due to mission requirements.

S4Pro will design and implement enabling technology for high-end data products produced on-board spacecraft through the implementation of a power efficient high performance space processing chain designed for low-Earth orbit (LEO) missions with a focus on Earth observation and satellite communication systems.

DIACAT aims to develop a completely new technology for the direct photocatalytic conversion of CO2 into fine chemicals and fuels using visible light. The approach utilises the unique characteristics of man-made diamond, now widely available at low economic cost, to generate solvated electrons upon light irradiation in solutions (e.g. in water and ionic liquids).

The main objective of BIOCON-CO2 is to develop and validate in industrially relevant environment a flexible platform to biologically transform CO2 into added-value chemicals and plastics.

VERIFY proposes to quantify more accurately carbon stocks and the fluxes of carbon dioxide (CO2), methane (CH4), and nitrous oxide (N2O) across the EU based on independent observations in support of inventories that rely only on statistical data.

In 2015 and 2016, the EU experienced an unparalleled influx refugees and migrants. This situation poses multiple challenges for social- and health services and labour markets in host communities as well as for the lives of the refugees. In response to this situation, the vision of FOCUS is to increase understanding of, and provide effective and evidence-based solutions for, the challenges of forced migration within host communities and thereby contribute to increased tolerance, peaceful coexistence, and reduced radicalization across Europe and in the Middle East.